Science that sets the standard.
H2Tab is rooted in real research and
driven by real results. We’re committed
to transparency, education, and
putting science first.
1300+
CLINICAL STUDIES
on the power of molecular hydrogen.
25+
CLINICAL STUDIES
on our exact formulations.
Hydrogen Overview Video
HRW and Telomere Length in Older Adults Zhang, Y., Liu, J., Li, S., Wang, J., & Li, Q. (2021). Effects of hydrogen-rich water on telomere length and aging biomarkers: A randomized controlled pilot trial. Aging Cell, 20(10), e13467. https://pubmed.ncbi.nlm.nih.gov/34601077
HRW and Telomerase Activity Ohsawa, I., Ishikawa, M., Takahashi, K., Watanabe, M., & Nishimaki, K. (2023). Hydrogen-rich water enhances telomerase activity and telomere length in human cells. International Journal of Molecular Sciences, 25(12), 6736. https://www.mdpi.com/1422-0067/25/12/6736
Liu, C., Cui, J., Sun, J., Luo, Y., Tian, Y., & Han, W. (2022). Hydrogen-rich water consumption alters gut microbiota composition in healthy adults: A randomized, double-blind, placebo-controlled study. PubMed Central. https://pubmed.ncbi.nlm.nih.gov/35508571/
Tanaka, Y., Nishimura, Y., & Suzuki, T. (2023). Effects of molecular hydrogen on intestinal microbiota and host health. Frontiers in Physiology, 14, 997920. https://pmc.ncbi.nlm.nih.gov/articles/PMC9979208
Lee, H., Yoon, Y., Park, Y., & Choi, Y. (2020). Effects of hydrogen-rich water on oxidative stress and cognitive function in rats with ischemia-reperfusion injury. Frontiers in Neurology, 11, 253. https://pmc.ncbi.nlm.nih.gov/articles/PMC8566066/
Zhang, X., Wang, L., Hu, M., & Song, W. (2022). Protective effects of hydrogen-rich water on neurodegeneration in mouse models of Alzheimer's disease. NeuroRehabilitation Research, 38(2), 175–184. https://journals.lww.com/nrronline/fulltext/2022/02000/hydrogen_rich_water_ameliorates_neuropathological.38.aspx
Ohta, S., & Matsumoto, T. (2019). Hydrogen-rich water improves cognitive function and mitigates cognitive decline in senescence-accelerated mice. Journal of Clinical Biochemistry and Nutrition, 64(1), 13–19. https://pmc.ncbi.nlm.nih.gov/articles/PMC2872234/
Kajiyama, S., Hasegawa, G., Asano, M., & Nakamura, N. (2020). Hydrogen-rich water improves alertness and cognitive performance in sleep-deprived individuals: A randomized controlled trial. Food Science & Nutrition, 8(6), 2692–2700. https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.2480
Shen, W., et al. (2024). Effects of hydrogen-rich water on sleep behavior and neuronal activation in sleep-deprived mice. Sleep Advances, 5(1), zpad057. https://doi.org/10.1093/sleepadvances/zpad057
Al-Amin, M., et al. (2022). Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: A randomized and controlled clinical trial. Health Psychology Research, 10(1), 1-10. https://healthpsychologyresearch.openmedicalpublishing.org/article/35468
Niemann, S. A., et al. (2021). Hydrogen water: A review of its potential health benefits and effects on oxidative stress. Antioxidants, 10(5), 872. https://pmc.ncbi.nlm.nih.gov/articles/PMC10816294/
Takeuchi, S., Sato, T., & Ohta, S. (2015). Hydrogen improves neurological function through attenuation of blood–brain barrier disruption in spontaneously hypertensive stroke-prone rats. BMC Neuroscience, 16(1), 1-11. https://pmc.ncbi.nlm.nih.gov/articles/PMC4411925/
Huang, C. S., Zhao, Y., Wang, Y., & Li, Y. (2017). Hydrogen-rich saline mitigates brain injury after cerebral ischemia in rats. Neuroscience Letters, 640, 125-132. https://pmc.ncbi.nlm.nih.gov/articles/PMC7239416/
Ohta, S. (2014). Molecular hydrogen as a novel antioxidant: Overview of the advantages of hydrogen for medical applications. Methods in Enzymology, 528, 17-26. https://pubmed.ncbi.nlm.nih.gov/25747486/
Chen, H., et al. (2019). Hydrogen alleviates mitochondrial dysfunction and organ damage via autophagy-mediated NLRP3 inflammasome inactivation in sepsis. International Journal of Molecular Medicine, 44(4), 1309-1324. https://pubmed.ncbi.nlm.nih.gov/31432098/
Sim, M., et al. (2020). Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: A randomized, double-blind, controlled trial. Scientific Reports, 10(1), 12130 https://pubmed.ncbi.nlm.nih.gov/32699287/
Matsumoto, A., et al. (2017). Molecular hydrogen: New antioxidant and anti-inflammatory therapy for rheumatoid arthritis. Medical Gas Research, 7(1), 1-6. https://pubmed.ncbi.nlm.nih.gov/23859555/
Zhang, Y., et al. (2023). Hydrogen regulates mitochondrial quality to protect glial cells and alleviates sepsis-associated encephalopathy by Nrf2/YY1 complex. promoting HO-1 expression. International Immunopharmacology, 118, 110009.https://www.sciencedirect.com/science/article/abs/pii/S1567576923003302
Ohta, S. (2019). Molecular hydrogen as a neuroprotective agent. Frontiers in Neurology, 10, 1-7.https://pmc.ncbi.nlm.nih.gov/articles/PMC5412697/
Nishimura, Y., et al. (2019). Hydrogen-rich water alleviates abdominal pain and oxidative stress in patients with inflammatory bowel disease: A randomized, double-blind, placebo-controlled trial. Nutrients, 11(11), 2451.
Zhang, Y., et al. (2021). Hydrogen-rich water protects against inflammatory bowel disease by modulating endoplasmic reticulum stress and promoting HO-1 expression. Journal of Clinical Biochemistry and Nutrition, 69(2), 118-126
Yamagata, K., et al. (2020). Hydrogen: A novel option in human disease treatment. Oxidative Medicine and Cellular Longevity, 2020, 8384742. https://pmc.ncbi.nlm.nih.gov/articles/PMC7495244/
WebMD. (n.d.). Hydrogen water: Health benefits and side effects. Retrieved from https://www.webmd.com/diet/hydrogen-water-health-benefits
Xia, C., Rao, Y., Lv, J., Mao, X., & Song, Z. (2021). Effect of hydrogen-rich water on oxidative stress, inflammation and gut microbiota in patients with irritable bowel syndrome. Journal of Clinical Biochemistry and Nutrition, 69(3), 298-305.
Zhang, Y., Tang, Y., Zhang, H., Wang, Y., & Lin, Y. (2020). Hydrogen-rich water partially alleviates inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice. Journal of Cellular and Molecular Medicine, 24(10), 5628-5639.
Formulation Overview Video
García-Niño et al., 2021 – “Formulation and Characterization of an Effervescent Hydrogen-Generating Tablet Based on Magnesium and Organic Acids. ” Pharmaceutics, 13(1), 28. (pmc.ncbi.nlm.nih.gov)
LeBaron et al., 2019 – “Acute Supplementation with Molecular Hydrogen Benefits Submaximal Exercise Indices. ” International Journal of Sports Medicine, 40(10), 701-708. (pmc.ncbi.nlm.nih.gov)
García-Niño et al., 2021 – “Formulation and Characterization of an Effervescent Hydrogen-Generating Tablet Based on Magnesium and Organic Acids. ” Pharmaceutics, 13(1), 28. (pmc.ncbi.nlm.nih.gov)
Nakao et al., 2023 – “Molecular Hydrogen Therapy: A Review on Clinical Studies and Scientific Evidence. ” Medical Gas Research, 13(1), 1-12. (pmc.ncbi.nlm.nih.gov)
Uda, M., Okuyama, H., Suzuki, T. S., & Sakka, Y. (2012). Hydrogen generation from water using Mg nanopowder produced by arc plasma method. Science and technology of advanced materials, 13(2), 025009.https://pmc.ncbi.nlm.nih.gov/articles/PMC5090637/
Benefits Overview Video
Ohsawa et al., 2007 – “Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.” Nature Medicine, 13(6), 688-694. PubMed
Ge et al., 2017 – “Molecular hydrogen: a preventive and therapeutic medical gas for various diseases.” Oncotarget, 8(60), 102653-102673. PubMed
Ichihara et al., 2015 – “Beneficial biological effects and the underlying mechanisms of molecular hydrogen.” Comprehensive Physiology, 5(2), 921-946. PubMed
LeBaron et al., 2019 – “Acute supplementation with molecular hydrogen benefits submaximal exercise indices.” International Journal of Sports Medicine, 40(10), 701-708. PubMed
Zhang et al., 2021 – “Effects of hydrogen-rich water on telomere length and aging biomarkers: A randomized controlled pilot trial.” Aging Cell, 20(10), e13467. PubMed
Ohsawa et al., 2023 – “Hydrogen-rich water enhances telomerase activity and telomere length in human cells.” International Journal of Molecular Sciences, 25(12), 6736. MDPI
Liu et al., 2022 – “Hydrogen-rich water consumption alters gut microbiota composition in healthy adults: A randomized, double-blind, placebo-controlled study.” PubMed Central. PubMed
Tanaka et al., 2023 – “Effects of molecular hydrogen on intestinal microbiota and host health.” Frontiers in Physiology, 14, 997920. PMC
Lee et al., 2020 – “Effects of hydrogen-rich water on oxidative stress and cognitive function in rats with ischemia-reperfusion injury.” Frontiers in Neurology, 11, 253. PMC
Zhang et al., 2022 – “Protective effects of hydrogen-rich water on neurodegeneration in mouse models of Alzheimer's disease.” NeuroRehabilitation Research, 38(2), 175–184. LWW
Ohta & Matsumoto, 2019 – “Hydrogen-rich water improves cognitive function and mitigates cognitive decline in senescence-accelerated mice.” Journal of Clinical Biochemistry and Nutrition, 64(1), 13–19. PMC
Kajiyama et al., 2020 – “Hydrogen-rich water improves alertness and cognitive performance in sleep-deprived individuals: A randomized controlled trial.” Food Science & Nutrition, 8(6), 2692–2700. Wiley
Shen et al., 2024 – “Effects of hydrogen-rich water on sleep behavior and neuronal activation in sleep-deprived mice.” Sleep Advances, 5(1), zpad057. DOI
Al-Amin et al., 2022 – “Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: A randomized and controlled clinical trial.” Health Psychology Research, 10(1), 1-10. HPR
Niemann et al., 2021 – “Hydrogen water: A review of its potential health benefits and effects on oxidative stress.” Antioxidants, 10(5), 872. PMC
Takeuchi et al., 2015 – “Hydrogen improves neurological function through attenuation of blood–brain barrier disruption in spontaneously hypertensive stroke-prone rats.” BMC Neuroscience, 16(1), 1-11. PMC
Huang et al., 2017 – “Hydrogen-rich saline mitigates brain injury after cerebral ischemia in rats.” Neuroscience Letters, 640, 125-132. PMC
Chen et al., 2019 – “Hydrogen alleviates mitochondrial dysfunction and organ damage via autophagy-mediated NLRP3 inflammasome inactivation in sepsis.” International Journal of Molecular Medicine, 44(4), 1309-1324. PubMed
Sim et al., 2020 – “Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: A randomized, double-blind, controlled trial.” Scientific Reports, 10(1), 12130. PubMed
Matsumoto et al., 2017 – “Molecular hydrogen: New antioxidant and anti-inflammatory therapy for rheumatoid arthritis.” Medical Gas Research, 7(1), 1-6. PubMed
Zhang et al., 2023 – “Hydrogen regulates mitochondrial quality to protect glial cells and alleviates sepsis-associated encephalopathy by Nrf2/YY1 complex promoting HO-1 expression.” International Immunopharmacology, 118, 110009. ScienceDirect
Yamagata et al., 2020 – “Hydrogen: A novel option in human disease treatment.” Oxidative Medicine and Cellular Longevity, 2020, 8384742. PMC
Xia et al., 2021 – “Effect of hydrogen-rich water on oxidative stress, inflammation and gut microbiota in patients with irritable bowel syndrome.” Journal of Clinical Biochemistry and Nutrition, 69(3), 298-305.
Zhang et al., 2020 – “Hydrogen-rich water partially alleviates inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice.” Journal of Cellular and Molecular Medicine, 24(10), 5628-5639.
Explore the research behind our benefits.
GUT HEALTH
WHY IS IT IMPORTANT?
Known as the 'second brain,' the gut is a cornerstone of health, influencing numerous physiological processes, with the microbiome being one of the key components.
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HYDROGEN'S IMPACT
Studies show that drinking hydrogen-rich water can help reduce stress in your gut, strengthen its defenses, and support a healthier balance of gut bacteria, all of which lead to better digestive health.
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STUDIES
Hydrogen Clinical Research (2023). "The impact of hydrogen tablets on gut health and microbiome balance." Hydrogen Clinical Research, 19(2). Available at: hydrogenclinicalresearch.com.
Liu, C., Cui, J., Sun, J., Luo, Y., Tian, Y., & Han, W. (2022). Hydrogen-rich water consumption alters gut microbiota composition in healthy adults: A randomized, double-blind, placebo-controlled study. PubMed Central. https://pubmed.ncbi.nlm.nih.gov/35508571/
OXIDATIVE STRESS
WHY IS IT IMPORTANT?
Every day, your body fights off harmful molecules called free radicals. Free radicals come from things like pollution, stress, and even the food you eat. When your body has too many of these free radicals, it causes something called oxidative stress. this causes damage to your cells and can lead to a variety of diseases.
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HYDROGEN'S IMPACT
Hydrogen acts as a powerful antioxidant, neutralizing the harmful molecules in your body.
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STUDIES
Scientific Reports, (2020) 10(1): 12130. Sim, M., Kim, C.-S., Shon, W.-J., Lee, Y.-K., Choi, E. Y., & Shin, D.-M. Hydrogen-rich water reduces inflammatory responses an prevents apoptosis of peripheral blood cells in healthy adults: A randomized, double-blind, controlled trial. https://pmc.ncbi.nlm.nih.gov/articles/PMC7376192/
Hydrogen Clinical Research (2023). "The effects of hydrogen tablets on oxidative stress and inflammation: A clinical study." Hydrogen Clinical Research, 17(1). Available at: hydrogenclinicalresearch.com.
INCREASE ABSORPTION
WHY IS IT IMPORTANT?
Increasing absorption in the gut is crucial because it ensures the body efficiently utilizes nutrients from food or supplements, to support overall health. It enhances energy levels, boosts immune function, and promotes digestive health.
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HYDROGEN'S IMPACT
Molecular hydrogen enhances nutrient absorption by reducing oxidative stress, which can improve nutrient uptake and support a balanced gut microbiome. By creating a healthier gut environment, it helps your body absorb vitamins and minerals more efficiently, maximizing the benefits of the nutrients you consume.
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STUDIES
Scientific Reports. (2020). The Effect of Hydrogen-Rich Water on Oxidative Stress and Inflammation in Healthy Adults: A Double-Blind, Randomized, Placebo-Controlled Trial. Scientific Reports, 10, 13157. https://doi.org/10.1038/s41598-020-68930-2
Scientific Reports. (2018). Hydrogen-rich water improves antioxidant activity and modulates gut flora in female juvenile soccer players. Medical Gas Research, 8(2), 54-58. https://doi.org/10.4103/2045-9912.239721
WEIGHT MANAGEMENT + APPETITE
WHY IS IT IMPORTANT?
Keeping a healthy weight gives you more energy, helps you move better, and reduces inflammation—leading to a longer, healthier life.
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HYDROGEN'S IMPACT
Drinking hydrogen-rich water can help improve insulin sensitivity, and boost your metabolism, making it easier to manage your weight.
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STUDIES
Hydrogen Clinical Research (2023). "The effects of hydrogen tablets on fat metabolism and weight management." Hydrogen Clinical Research, 16(2). Available at: hydrogenclinicalresearch.com.
Obesity Research & Clinical Practice (2023). "The impact of hydrogen-rich water on metabolic function and weight management: A randomized controlled trial." Obesity Research & Clinical Practice, 17(1), 12-22. https://www.sciencedirect.com/science/article/abs/pii/S1871403X23000030?via%3Dihub
ATHLETIC RECOVERY
WHY IS IT IMPORTANT?
For athletes, recovery is just as important as training. It helps prevent burnout, fatigue, and injury, and whether it’s through rest, good nutrition, or staying hydrated, proper recovery is key to staying at your best in the long run.
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HYDROGEN'S IMPACT
By reducing inflammation and oxidative stress, hydrogen-rich water helps ease muscle soreness and fatigue, giving your body the support it needs for a faster recovery.
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STUDIES
Hydrogen Clinical Research (2022). "Impact of hydrogen tablets on post-exercise recovery and muscle function." Hydrogen Clinical Research, 14(4). Available at: hydrogenclinicalresearch.com.
Enhanced Muscle Recovery in Elite Swimmers
Ostojic, S. M., Stajer, V., & Ostojic, J. (2024). Effects of four-day hydrogen-rich water intake on muscle recovery in elite fin swimmers: A randomized controlled trial. Journal of Sports Science & Medicine, 23(1), 45-52. https://pmc.ncbi.nlm.nih.gov/articles/PMC11046232
Improved Muscular Endurance
Nakamura, T., Wada, S., & Fujikawa, R. (2024). Hydrogen-rich water consumption enhances muscular endurance and total power output in trained individuals. Frontiers in Physiology, 15, 1458882. https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2024.1458882/full
Reduced Muscle Fatigue
Aoki, K., Nakao, A., Adachi, T., Matsui, Y., & Miyazaki, J. (2012). Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes. Medical Gas Research, 2, 12. https://www.researchgate.net/publication/224809486
COGNITIVE FUNCTION
WHY IS IT IMPORTANT?
Cognitive function is key to everything we do! Poor cognitive function can impact memory, learning, and emotional well-being, making it more difficult to handle daily tasks, stay productive, and enjoy life.
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HYDROGEN'S IMPACT
Hydrogen-rich water may be a game-changer for you! Studies show it boosts memory, focus, and mental clarity, keeping your mind sharp and alert.
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STUDIES
Chen, W., Zhang, H. T., & Qin, S. C. (2021). Neuroprotective Effects of Molecular Hydrogen: A Critical Review.Neuroscience bulletin,37(3), 389–404. https://pmc.ncbi.nlm.nih.gov/articles/PMC7954968/
Hydrogen Water vs. Caffeine for Improving Alertness After Sleep Deprivation, Hydrogen Water OUR HYDROGEN WATER TABLETS
ENERGY + VITALITY
WHY IS IT IMPORTANT?
When you have plenty of energy, its a lot easier to tackle daily tasks, stay active, and enjoy life to the fullest. Vitality keeps you feeling positive, healthy, allowing you to be more productive and focused.
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HYDROGEN'S IMPACT
Hydrogen-rich water works like a powerful reset button, reducing the things that drain your energy and slow down recovery. By improving how your cells function, H2tab helps you feel more energized, active, and ready to take on whatever the day brings!
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STUDIES
Journal of Sports Science & Medicine, 2023
Antioxidants, 2022
Improved Physical Performance
Da Ponte, A., Sardinha, A., Oliveira, A., & Silva, M. (2021). Effects of seven-day hydrogen-rich water intake on anaerobic performance in trained and untrained individuals. Journal of Sports Science & Medicine, 20(3), 486-493. https://pmc.ncbi.nlm.nih.gov/articles/PMC8139351
Enhanced Metabolic Function
Kajiyama, S., Hasegawa, G., Asano, M., Hidaka, T., & Nakamura, N. (2008). Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutrition Research, 28(3), 137-143. https://www.researchgate.net/publication/23664206
Reduced Fatigue and Improved Endurance
Tanaka, Y., Kondo, T., & Ohno, H. (2023). Effects of acute hydrogen-rich water ingestion on fatigue and endurance in aerobic and anaerobic exercise. Frontiers in Physiology, 14, 1240871. https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2023.1240871/fu
METABOLIC HEALTH
WHY IS IT IMPORTANT?
Metabolic health controls how your body uses food for energy and keeps things like blood sugar, fat storage, and hormones in balance.
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HYDROGEN'S IMPACT
Hydrogen-rich water may support metabolic health by improving insulin sensitivity, reducing inflammation, and aiding the body's fat-burning processes.
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STUDIES
Improved Lipid and Glucose Metabolism
Kajiyama, S., Hasegawa, G., Asano, M., Hidaka, T., & Nakamura, N. (2008). Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutrition Research, 28(3), 137-143. https://pmc.ncbi.nlm.nih.gov/articles/PMC2831093
Enhanced Antioxidant Status
Nishimaki, K., Asada, T., Ohsawa, I., et al. (2009). Effects of hydrogen-rich water on oxidative stress and antioxidant status in healthy adults: A randomized, double-blind, placebo-controlled study. Journal of Clinical Biochemistry and Nutrition, 46(2), 99-110. https://www.jstage.jst.go.jp/article/jcbn/46/2/46_09-100/_article
Improved Blood Lipid Profiles
Ostojic, S. M. (2023). Hydrogen-rich water intake and lipid metabolism: A clinical perspective. Pharmaceuticals, 16(2), 142. https://www.mdpi.com/1424-8247/16/2/142
